Yu-di Liao and Zhen-ran Jiang* Pages 446 - 449 ( 4 )
Background: With the declining trend of new drugs yield each year, more comprehensive knowledge of drug MoAs can help identify new applications of available drugs and discovery novel mechanism of drug action.
Objective: Therefore, construction of a specialized drug mode of action (MoA) database is of paramount importance for new drug research & development.
Methods: This paper introduces an integrated database for drug mode of action knowledge (MoABank).
Results: This database can provide the knowledge about drug MoAs, targets, pathways, side effects and other drug-related information for researchers.
Conclusion: We believe MoABank can make it more convenient for users to obtain the drug MoA information in the future.
Information integration, MoA, database, drug molecular, cheminformatics, bioactivity data.
Department of Computer Science and Technology, East China Normal University, Shanghai, 200062, Department of Computer Science and Technology, East China Normal University, Shanghai, 200062